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Through mitosis, the 23 pairs of human chromosomes condense and therefore are visible with a light-weight microscope. A karyotype Examination ordinarily includes blocking cells in mitosis and staining the condensed chromosomes with Giemsa dye. The dye stains areas of chromosomes which are full of the base pairs Adenine (A) and Thymine (T) manufacturing a dark band.
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This physical exercise is actually a simulation of human karyotyping using electronic pictures of chromosomes from true human genetic research. You'll be arranging chromosomes into a finished karyotype, and interpreting your results equally as in case you were being Performing inside of a genetic analysis plan at a medical center or clinic.
This workout is built as an introduction to genetic experiments on humans. Karyotyping is among quite a few approaches that enable us to look for quite a few thousand doable genetic diseases in people. You may Consider three sufferers' case histories, entire their karyotypes, and diagnose any lacking or extra chromosomes.